GrainGenes Reference Report: COH-15-649
Reference
COH-15-649
Title
Snf2-family proteins: chromatin remodellers for any occasion
Journal
Current Opinion in Chemical Biology
Year
2011
Volume
15
Pages
649-656
Remark
Discusses transcription factor / regulator : SNF2
Author
Ryan DP Owen-Hughes T
Abstract
Chromatin facilitates the housing of eukaryotic DNA within the nucleus and restricts access to the underlying sequences. Thus, the regulation of chromatin structure provides an excellent platform for regulating processes that require information stored within genomic DNA. Snf2 proteins are a family of helicase-like proteins that direct energy derived from ATP hydrolysis into the mechanical remodelling of chromatin structure. Here, we highlight some of the recent discoveries regarding this family of proteins and show Snf2 proteins have roles in many aspects of genetic metabolism. Recent developments include new insights into the mechanism for nucleosome spacing and histone dimer exchange; together with growing evidence for the involvement of Snf2 proteins in DNA repair.
External Databases
https://www.ncbi.nlm.nih.gov/pubmed/21862382
GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.
GrainGenes Reference Report: COH-15-649
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GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture. | |||