GrainGenes Sequence Report: CP001129_1307.cds
Sequence
CP001129_1307.cds
Structure From Source
CP001129
Source Exons
1 933
Gene
hprK
Gene Product
HPr kinase/phosphorylase HprK
Remark
CDS note: similar to gb|ABF33543.1| HPR(SER) kinase/phosphatase [Streptococcus pyogenes MGAS10270]; Catalyzes the ATP- as well as the pyrophosphate- dependent phosphorylation of a specific serine residue in HPr, a phosphocarrier protein of the phosphoenolpyruvate-dependent sugar phosphotransferase system (PTS). HprK/P also catalyzes the pyrophosphate-producing, inorganic phosphate-dependent dephosphorylation (phosphorolysis) of seryl-phosphorylated HPr (P- Ser-HPr). The two antagonistic activities of HprK/P are regulated by several intracellular metabolites, which change their concentration in response to the absence or presence of rapidly metabolisable carbon sources (glucose, fructose, etc.) in the growth medium. Therefore, by controlling the phosphorylation state of HPr, HPrK/P is a sensor enzyme that plays a major role in the regulation of carbon metabolism and sugar transport:it mediates carbon catabolite repression (CCR), and regulates PTS-catalyzed carbohydrate uptake and inducer exclusion. DB_xref: GI:195975168 Feature: CDS: locus_tag = 'Sez_1358'; transl_table = 11; protein_id = 'ACG62694.1'; On complementary strand.
Codon Start
1
GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture.
GrainGenes Sequence Report: CP001129_1307.cds
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GrainGenes is a product of the Agricultural Research Service of the US Department of Agriculture. | |||