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GrainGenes Sequence Report: CP001129_1370.cds

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Sequence
CP001129_1370.cds
Structure From Source
CP001129
Source Exons
1891
Gene
mutM
Gene Product
formamidopyrimidine-DNA glycosylase MutM
Remark
CDS note: similar to ref|YP_059752.1| formamidopyrimidine-DNA glycosylase [Streptococcus pyogenes MGAS10394]; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates.
DB_xref: GI:195975231
Feature: CDS: locus_tag = 'Sez_1423'; transl_table = 11; protein_id = 'ACG62757.1'; On complementary strand.
Codon Start
1

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